September 19, 2012
MHC Ceus “We show that circuits normally involved in emotion, as well as cognition, are disrupted when this single transcription factor is activated,” Duman explains. These findings may point toward a new target for treatment. “We hope that by enhancing synaptic connections, either with novel medications or behavioral interventions, we can develop more effective antidepressant therapies,” says Duman. — by Helen Fields Related Links: Depression: http://www.nimh.nih.gov/health/topics/depression/index.shtml More Young Neurons Equals Better Brain Function: http://www.nih.gov/researchmatters/april2011/ 04112011brainfunction.htm Brain Basics: Know Your Brain: http://www.ninds.nih.gov/disorders/brain_basics/know_your_brain.htm Reference: Nat Med. 2012 Aug 12. [Epub ahead of print] PMID: 22885997.